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Santo Domingo to Santiago de Cuba flights

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Why book with Opodo?
  • Cheap flights with over 660 airlines
  • Compare the best deals
  • Fly to Santiago de Cuba for low prices
Flight Duration Flights between Santo Domingo and Santiago de Cuba take, on average, 1 h and 40 m minutes, but the time can vary according to other factors
Cheapest flight Cheapest price for a one-way flight between Santo Domingo with Santiago de Cuba found by our customers in the last 72 hours
Departing Airport The airport Las Americas is the departure airport operating flights between Santo Domingo and Santiago de Cuba
Arriving Airport Flights departing Santo Domingo with Santiago de Cuba as destination arrives at Antonio Maceo

Cheap last minute flights to Santiago de Cuba

Latest deals and top flight routes from Santo Domingo airports.

Departure Mon, 29 Aug Return Thu, 01 Sep
SDQ Santo Domingo
SCU Santiago de Cuba
return from £887
Departure Thu, 08 Sep Return Thu, 15 Sep
SDQ Santo Domingo
SCU Santiago de Cuba
return from £908
Flight route information
Find out further information on Santo Domingo and Santiago de Cuba to help you prepare for your trip.
Santo Domingo airports
  • ( Las Americas (SDQ)
    How far from city centre: 21 miles
  • ( Herrera (HEX)
    How far from city centre: 21 miles
Santiago de Cuba airports
  • ( Antonio Maceo (SCU)
    How far from city centre: 5 miles
K Distance: 395 miles

Search for flights from Santo Domingo to Santiago de Cuba

Find cheap flights from Santo Domingo to Santiago de Cuba with the Opodo search engine. Whether it’s on business, for a relaxing holiday or to visit loved ones, you will find all the best deals on flights from Santo Domingo with Opodo, featuring cheap flights by all the top low cost and standard airlines. By simply entering your preferences in our speedy search engine, a large selection of options will be returned from which you just need to select the best deal that works for you. We’ll do the rest! Alternatively, if you are flexible on dates or an early bird, discover the cheapest day to fly from Santo Domingo to Santiago de Cuba to ensure you get the best price. Find exclusive discounts by downloading the Opodo App and subscribing to our newsletter to stay in touch with the best offers on flights, hotels and more. Finally, don’t forget to book a hotel or car hire to complete your journey, all of which you will find on Opodo, your one-stop travel shop. Then just sit back and relax and enjoy your holidays!

Frequent asked questions about flights from Santo Domingo to Santiago de Cuba

😷 Is it safe to travel from Santo Domingo to Santiago de Cuba during the Covid-19 situation?
At Opodo we want to make sure that your travel plans are not affected by any cancelation as well as any possible restrictions Cuba may apply when travelling from Santo Domingo. Is your flight cancelled? We've got your back! With our flexible ticket guarantee you can decide if you want to book another flight - free of rebooking fee - or get a full refund!
🔍 How can I find cheap flights from Santo Domingo to Santiago de Cuba at Opodo?
The cheapest price for a flight from Santo Domingo to Santiago de Cuba is 887£. At Opodo we use different machine learned based methodologies to find our costumers the best option available, considering airline combinations, stopovers and direct flights as well as different criteria for inbound and outbound journeys.
📉 When is the best time to book a flight from Santo Domingo to Santiago de Cuba?
The most popular months to book a trip from Santo Domingo to Santiago de Cuba are April, October and November, based on the searches of our customers.
📅 When is the best time to travel from Santo Domingo to Santiago de Cuba?
The best time of the year to go to Santiago de Cuba when flying from Santo Domingo depends on several preference factors like climate, seasonality and, of course, price. When it comes to popularity, April is the top 1º month to fly to Santiago de Cuba from Santo Domingo in terms of searches from our customer, followed by February and December. If you prefer to avoid high peaks of turism, however, and escape a crowded period, January, December and February are the months with less volume of searchs for the route Santo Domingo -  Santiago de Cuba.
🕑 How long does the flight take to go from Santo Domingo to Santiago de Cuba?
The total flight time between Santo Domingo and Santiago de Cuba is of around 01:40 hours on average, considering an average distance of 673 km, for both direct and indirect flights for the route (which may have 1 or more stops in other cities in between).
🌡️ How is the weather in Santiago de Cuba compared to Santo Domingo?
While in Santo Domingo the temperatures can reach an average of 33.51 ºC in summer, with precipitation levels up to 12.0 mm ,Santiago de Cuba's temperatures can go up to 34.03 ºC during the hot season, with 6.0 mm average of rain rate . In winter, however, weather indicators show around 18.06 ºC in Santiago de Cuba, compared to the 16.48 ºC average degrees reported in Santo Domingo. During the winter period, Santo Domingo can register 12.0 mm precipitation, while Santiago de Cuba have an average of 3.0 mm rain level.
🛄 Which airports have flights between Santo Domingo and Santiago de Cuba?
The main airport route flying between Santo Domingo and Santiago de Cuba is: Las Americas (SDQ) to Antonio Maceo (SCU). This route is covered by the following airline(s):
  • Cubana De Aviacion.
  • InterCaribbean Airways.
Other popular routes

Other city destinations

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Our International travel websites

Flüge von Santo Domingo nach Santiago de Cuba
Vols de Saint-Domingue à Santiago de Cuba
Vuelos desde Santo Domingo a Santiago de Cuba